More on hypermetabolism

I had mentioned about a week or two ago that I was going to begin a blog series on the biology of eating disorders. I wanted to start with something about the causes of EDs or something like that, but I think this topic is extremely relevant and so we can just call this the first post in the series.

I did some more research tonight into the biology and etiology of hypermetabolism. So let's start with a basic definition from Wikipedia:

Hypermetabolism is the physiological state of increased rate of metabolic activity. The impact of the hypermetabolic state on patient nutritional requirements is often understated or overlooked. Hypermetabolism typically occurs after significant insult to the body. In hospitals and institutions, the most common causes are infections, sepsis, burns, multiple trauma, fever, long-bone fractures, hyperthyroidism, prolonged steroid therapy, surgery and bone marrow transplants.

And, yes, eating disorders. Specifically anorexia. As someone falls deeper and deeper into anorexia, their metabolic rate slows dramatically. During the Minnesota Starvation Study, resting energy expenditure (also known as basal metabolic rate- the amount of calories needed just to keep your body functioning and doesn't include ANY physical activity) fell by about one-third. The book "Introduction to Clinical Nutrition" says that

Starvation involves metabolic alterations that enhance the chance of survival by increasing the use of body fat stores, by sparing the use of glucose, by minimizing nitrogen loss, and by decreasing energy expenditure.

But when the ill person begins eating again, their metabolism kicks into high gear. Body temperature rises. A person can experience night sweats, which may also be related to hormone function returning to normal.

Why? It seems a remarkably inefficient use of resources. And indeed, hypermetabolism may not be entirely adaptive from an evolutionary standpoint as the body's use of food becomes remarkably inefficient. Even so, the body needs tremendous amounts of energy to replace lost fat and muscles stores, depleted organs, bone mass, hair, nails, you name it. No organ system is spared during an eating disorder.

The amount of calories needed for people with anorexia to return to a healthy weight can vary by illness severity (a lower BMI means more calories, as well as duration of illness), and by illness subtype. One study found that those with the binge-purge subtype of anorexia needed significantly fewer calories than those with the restricting subtype; another study found that calories were about the same. Other variants include your metabolic rate before illness onset. I've known several good friends curse their fast metabolisms quire vociferously during refeeing.

When looking at the phase after weight restoration, caloric needs between people with anorexia nervosa and those with bulimia nervosa turn out to be quite different. One study found that people with AN needed more calories per kilogram of body weight than normal controls, while those with BN needed fewer. It appears that people with a current diagnoses of BN but a history of AN require more calories than those with BN alone. Further, people with the restricting type of AN needed more calories than those with the binge-purge type, both of which were greater than patients with BN (some of the studies cited above show that, for weight maintenance, caloric needs are basically the same for any patient with a current diagnosis of AN).

Some of these differences may rest in premorbid differences in metabolic rate. It makes intuitive sense that a person who finds it easy to lose weight would have a faster innate metabolism. Other reasons calorie needs may remain unusually high for a person even after weight restoration is the sheer amount of rebuilding the body needs to perform. Bulimia is violently destructive to the body, and I would never say differently. However, some of the damage done by anorexia is slightly different, and the body must rebuild and repair essentially every organ in the body. My psychiatrist told me that the nerves continue to repair themselves for up to two years after weight restoration. This can hardly be the only organ system taking a long time to recover.

How long hypermetabolism lasts will probably vary from person to person, and depends on how long you were sick, how your body responded to the damage from your eating disorder, your activity levels, among others. There's no real way to be sure. If your caloric needs are unusually high--even for hypermetabolism--you can have body composition analysis and resting energy expenditure testing done. Personally, I think this is best left to extreme cases since so many of us have a tendency to fixate on numbers.

I hope this helps explain hypermetabolism just a little bit. I can't answer every question, as it's been a long time since my college biochemistry days, but I can always look things up.

1,013 comments:

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Suntran Matthew said...


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Suntran Matthew said...


I am so Happy to be writing this article in here, i am here to explore blogs forum about the wonderful and most safe cure for HERPES SIMPLEX VIRUS.I was positive to the Virus called HERPES and i lost hope completely because i was rejected even by my closet friends. i searched online to know and inquire about cure for HERPES and i saw testimony about DR Ebhota online on how he cured so many persons from Herpes Disease so i decided to contact the great herbalist because i know that nature has the power to heal everything. i contacted him to know how he can help me and he told me never to worry that he will help me with the natural herbs from God! after 2 days of contacting him, he told me that the cure has been ready and he sent it to me via FEDEX or DHL and it got to me after 4 days! i used the medicine as he instructed me (MORNING and EVENING) and i was cured! its really like a dream but i'm so happy! that's the reason i decided to also add more comment of Him so that more people can be saved just like me! and if you need his help,contact his Email: (drebhotasoltion@gmail.com) You can contact him on WhatsApp +2348089535482 He also have the herb to cure difference cure for any sickness (1) HERPES,
(2) DIABETES,
(3) HIV&AIDS,
(4) URINARY TRACT INFECTION,
(5) HEPATITIS B,
(6) IMPOTENCE,
(7) BARENESS/INFERTILITY
(8) DIARRHEA
(9) ASTHMA.. 

mr job said...

i want to inform the public how i was cured of HERPES Simplex Virus by a Doctor called Dr.EBHOTA. i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how Doctor EBHOTA cured them. I Was scared because i never believed in the Internet but i was convince to give him a try because i was having no hope of been cured of HERPES so i decided to contact him on his email, i searched his email on net and i saw a lot of people testifying about his goodness. when i contacted him he gave me hope and send a Herbal medicine to me that i took and it seriously worked for me, am a free person now without problem, my HERPES result came out negative. You can contact him on
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7 To Lose your wath
8 to enlargement of pennis
9. CANCER
10. ALS (Lou Gehrig's disease)
11 Hepatitis B
12 chronic pancreatic
13 emphysema
14 COPD (chronic obstructive pulmonary disease)   

mr job said...

i want to inform the public how i was cured of HERPES Simplex Virus by a Doctor called Dr.EBHOTA. i visited different hospital but they gave me list of drugs like Famvir, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how Doctor EBHOTA cured them. I Was scared because i never believed in the Internet but i was convince to give him a try because i was having no hope of been cured of HERPES so i decided to contact him on his email, i searched his email on net and i saw a lot of people testifying about his goodness. when i contacted him he gave me hope and send a Herbal medicine to me that i took and it seriously worked for me, am a free person now without problem, my HERPES result came out negative. You can contact him on
his Email: drebhotasolution@gmail.com or whatsapp him on +2348089535482 and get all your problem solved.
1Sickness of any kind
2 Help to CURE Hepatitis B, HIV/AIDs CANCER and BIPOLAR
3 Divorce, Breakup problem and To Re-unit
4 Pregnancy problem
5 Financial problem and Job promotion
6 To get a good and rich life partner
7 To Lose your wath
8 to enlargement of pennis
9. CANCER
10. ALS (Lou Gehrig's disease)
11 Hepatitis B
12 chronic pancreatic
13 emphysema
14 COPD (chronic obstructive pulmonary disease)   

Amanda Bella said...

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FINALLY FREE FROM HERPES VIRUS.
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Steven Young said...

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Steven Young said...

Thank you so much doctor Moahmmed for curing my GENITAL HERPES VIRUS, is good given a herbal  medicine a try, i am so happy today about my result, herpes virus has a cure i have confirm it now with my own cases, i have been reading different comment about people who are cured from herpes virus, ALS, HPV, CANCER, LUPUS VIRUS and many more with doctor mohammed herbal medicine , i was kind of skeptical so i made up my mid to give him a chance to cure me to to see if the comment i read was legit, i am 100% cure of this virus and i am giving my own comment base on my agreement with this doctor that once i am cure i will give a Testimony. pleases contact this doctor on your cure WHATSAPP/CALL +2349036036397 EMAIL  herbalcure12@gmail.com  i am very lucky been among people giving a comment about this great doctor, before i was a comment ready. am grateful for this massive cure of my health. thanks very much 

anna lucas said...

Hello viewer’s
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Grace Edmond said...

Dr Moses Herbal medicine is a good remedy for herpes simplex virus cure. i want to inform the public how i was cured from (HERPES SIMPLEX VIRUS) by DR Moses, i visited different hospital but they gave me list of drugs like Familiar, Zovirax, and Valtrex which is very expensive to treat the symptoms and never cured me. I was browsing through the Internet searching for remedy on HERPES and i saw comment of people talking about how DR Moses cured them, when i contacted him he gave me hope and send a Herbal medicine via UPS ( Delivery service ) to me and i drank it, seriously it worked for me, am a free person now without any problem, my HERPES result came out negative... Contact him if you need his assistance email him ehichioyaspelltemple@gmail.com or whatsapp him on +2348057508654 

Tom Grant said...

Is any one here suffering from any kind of STD or STI ? , Now this is to everyone out there with different health challenges, as I know there are still a lot of people suffering from different health issues and are therefore looking for solution. I bring you Good news. There is a man called Dr. Tokubo a herbal practitioner who helped cure me from Genital herpes, this i had suffered from for the past 2years and have spent so much money trying to survive from it. I got my healing by taking the herbal medicine he sent to me to drink for about 9days . 3days after completion of the dosage, I went for a medical checkup and I was tested Genital Herpes NEGATIVE. I'm sharing this so that other people can know of this great healer called Dr Tokubo because I got to know him through a friend he cured from HIV. I was made to understand that he can cure several other deadly diseases and infections. Don't die in ignorance and don't let that illness take your life. Contact Dr. Tokubo through: drtokubotemple@gmail.com You can also call/whatsapp him on:+2349037990322 Thank you dr tokubo. Be kind enough to share your testimonies as you received your cure.he is good too to cure all type of disease and virus.1 HIV cure
2 cancer
3 diabetes
4 hepatitis
5 herpes.
You can contact him if you are having any disease or infection problem...

patrick morrison said...

HOW I GOT CURED OF HERPES DISEASE
I'm here to testify about what DR. ANUGE did for me. I have been suffering from (HERPES) disease for the past 5 years and had constant pain,especially inside my body. During the first year,I had faith in God that i would be healed someday. This disease started circulating all over my body and i have been taking treatment from my doctor, few weeks ago i came across a testimony of one lady on the internet testifying about a Man called DR. Anuge on how he cured her from herpes disease. And she also gave the email address of this man and advise anybody to contact him for help for any kind of sickness that he would be of help.so I emailed him telling him about my (HERPES) he told me not to worry that i was going to be cured!! Well i never believed it,, well after all the procedures and remedy given to me by this man few weeks later i started experiencing changes all over me as DR. ANUGE assured me that i will be cured,after some time. i went to my doctor to confirmed if i have be finally healed behold it was TRUE, the test came out negative. So friends my advise is if you have such sickness or any other at all you can contact DR. Anuge for help. Email} dranuge@gmail.com WhatsApp /call +2348164866838

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I'm a science writer, a jewelry design artist, a bookworm, a complete geek, and mom to a wonderful kitty. I am also recovering from a decade-plus battle with anorexia nervosa. I believe that complete recovery is possible, and that the first step along that path is full nutrition.

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Have any questions or comments about this blog? Feel free to email me at carrie@edbites.com



nour·ish: (v); to sustain with food or nutriment; supply with what is necessary for life, health, and growth; to cherish, foster, keep alive; to strengthen, build up, or promote



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